Multiple Applications of ADaM Time-to-Event Datasets

The CDISC ADaM team recently created guidelines for Time to Event (TTE) datasets. In the guidelines, a TTE dataset is specifically used to support survival analysis. This paper demonstrates that the TTE dataset can be used to support Exposure-Adjusted Incidence Rate (EAIR) analysis. This exploratory use of the ADaM TTE datasets structure filled a void in the CDISC ADaM analysis dataset structure for EAIR analysis. Detailed procedure and code for generating an EAIR analysis dataset will be presented. In addition, step-by-step instructions for generating a TTE analysis dataset and survival analysis result will also be covered in this paper.