Schizonellin A and B, new glycolipids from Schizonella melanogramma
1980
Abstract Two new glycolipids, schizonellin A and B, were isolated from cultures of the smut fungus Schizonella melanogramma . Their structures were elucidated by chemical degradation and spectroscopic methods. The schizonellins are active against Gram-positive bacteria, as well as against some Gram-negative bacteria and some fungi. DNA-, RNA- and protein-syntheses in Ehrlich carcinoma ascitic cells are inhibited simultaneously after addition of the schizonellins. Strong haemolytic action on bovine erythrocytes was observed.
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