Association of L-Ficolin Levels and FCN2 Genotypes with Chronic Chagas Disease

Paola R. Luz,Angelica Beate Winter Boldt,Caroline Grisbach,Jürgen F. J. Kun,Thirumalaisamy P. Velavan,I. J. T. Messias-Reason

Association of L-Ficolin Levels and FCN2 Genotypes with Chronic Chagas Disease

2013

Paola R. Luz
Angelica Beate Winter Boldt
Caroline Grisbach
Jürgen F. J. Kun
Thirumalaisamy P. Velavan
I. J. T. Messias-Reason

Background L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system.

Keywords:

Chagas disease
Microbiology
Genotype
Allele
Ficolin
Immunology
Biology
Complement system
Polymerase chain reaction
Trypanosoma cruzi
Phagocytosis
Haplotype

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