Chemosensitivity Assessed by Collagen Gel Droplet Embedded Culture Drug Sensitivity Test, and MDR1, MRP1, and MRP2 mRNA Expression in Human Colorectal Adenocarcinomas

Takako Nakahara,Toshiyuki Sakaeda,Tsutomu Nakamura,Takao Tamura,Chiharu Nishioka,Nobuo Aoyama,Noboru Okamura,Toshiro Shirakawa,Akinobu Gotoh,Takashi Kamigaki,Masakazu Ohno,Yoshikazu Kuroda,Masafumi Matsuo,Masato Kasuga,Katsuhiko Okumura

Chemosensitivity Assessed by Collagen Gel Droplet Embedded Culture Drug Sensitivity Test, and MDR1, MRP1, and MRP2 mRNA Expression in Human Colorectal Adenocarcinomas

2004

Takako Nakahara
Toshiyuki Sakaeda
Tsutomu Nakamura
Takao Tamura
Chiharu Nishioka
Nobuo Aoyama
Noboru Okamura
Toshiro Shirakawa
Akinobu Gotoh
Takashi Kamigaki
Masakazu Ohno
Yoshikazu Kuroda
Masafumi Matsuo
Masato Kasuga
Katsuhiko Okumura

Purpose. To evaluate chemosensitivity and its correlation with expression levels of the multidrug resistant transporter (MDR1) and the multidrug resistance-associated proteins 1 and 2 (MRP1, MRP2) mRNA in human colorectal adenocarcinomas.

Keywords:

Drug
Mitomycin C
Multidrug resistance-associated protein 2
Multiple drug resistance
Gemcitabine
Transporter
Cancer research
Messenger RNA
Multidrug Resistance-Associated Protein 1
Pathology
Biochemistry
Chemistry
sensitivity test

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