Burden of Coronavirus Disease-19 on cardiovascular system

The rapid emergence and spread of coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into a worldwide pandemic has caused unprecedented crisis on already overwhelmed healthcare system and global economy leading to healthcare and social emergency. Since its outbreak, the disease prognosis has largely been influenced by multisystem involvement. Comorbid conditions such as cardiovascular diseases have been the most common risk factor for its severity and outcome. Although the exact mechanism of myocardial involvement in patients with COVID-19 is unknown, several plausible mechanisms have been proposed, of which uncontrolled and dysregulated immune response is most implicated in its causation. In the present article, an attempt has been made to summarize the literature available on COVID-19 and its impact on the cardiovascular system.