Amino- and azidotrifluoromethylation of alkenes

Abstract Trifluoromethylation of alkenes has long been the interest of synthetic chemists. It is not only because of the great importance of F-containing compounds, but also on account of the pleasure of cracking the challenges in methodology development in this field. In particular, amino- and azidotrifluoromethylation of alkenes have recently been developing in a fast speed. This digest mainly deals with this advancement in racemic copper- and photocatalyzed amino- and azidotrifluoromethylation of alkenes while giving special highlight on our recent breakthrough on the copper-catalyzed asymmetric aminotrifluoromethylation reaction.