Morphology and Structure Properties of PEG-b-PBT, PEG-b-PBT-HA Nanofibers Based Gas-Electrospun

The block copolymer solutions were prepared by dissolving polyethylene glycol/polybutylene terephthalate (PEG-b-PBT) with different intrinsic viscosities in chloroform. The composite ultrafine nanofibers of PEG-b-PBT and PEG-b-PBT-HA(hydroxyapatite) were obtained by gas-electrospun, and were characterized by scanning electron microscopy (SEM), horizontal attenuated total reflectance for Fourier transform infrared spectrometer (HATR-FTIR), dynamic contact angle measuring apparatus and differential scanning calorimetry (DSC). The gas-electrospun fibrous membranes, which were made of ultrafine fibers with average diameter 180-1200nm and well-interconnected pores, were possessed with high surface-to-volume ratio and excellent hydrophilicity. The above results strongly suggest that fibrous membranes combine advantages of synthetic biodegradable polymers and nanometer-scale dimension for mimicking the natural ECM, and may represent an ideal tissue engineering scaffold, particularly for soft tissue, such as skin and cartilage tissue engineering scaffold.