Establishment of a Quick and Highly Accurate Breath Test for ALDH2 Genotyping

OBJECTIVES:Acetaldehyde, the first metabolite of ethanol, is a definite carcinogen for the esophagus, head, and neck; and aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that catalyzes the metabolism of acetaldehyde. TheALDH2genotype exists asALDH2*1/*1(active ALDH2),ALDH2*1/*2(heterozygo