The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression

* Manuscript Kenny, Lee et al. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression Paraic A. Kenny* ,1 , Genee Y. Lee* ,1 , Connie A. Myers 1,3 , Richard M. Neve 1 , Jeremy R. Semeiks 1 , Paul T. Spellman 1 , Katrin Lorenz 1,4 , Eva H. Lee 1 , Mary Helen Barcellos-Hoff 1 , Ole W. Petersen 2 , Joe W. Gray 1 , Mina J. Bissell 1 *These authors contributed equally to this report. Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA. 2 Structural Cell Biology Unit , Institute of Medical Anatomy, The Panum Institute, University of Copenhagen, DK-2200 Copenhagen N, Denmark. Address for correspondence: Mina J. Bissell. Tel: +1 510 486 4365; Fax: +1 510 486 5586; Email: mjbissell@lbl.gov Running title 3D breast cancer cell transcriptomes and morphologies Current address: Division of Neuropathology, Washington University School of Medicine, St. Louis, MO 63110 Department of Molecular Medicine, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany