Ptychographic optical coherence tomography
2021
Ptychography is a robust computational imaging technique that can
reconstruct complex light fields beyond conventional hardware limits.
However, for many wide-field computational imaging techniques, including
ptychography, depth sectioning remains a challenge. Here we demonstrate a
high-resolution three-dimensional (3D) computational imaging approach,
which combines ptychography with spectral-domain imaging, inspired by
optical coherence tomography (OCT). This results in a flexible imaging
system with the main advantages of OCT, such as depth-sectioning without
sample rotation, decoupling of transverse and axial resolution, and a high
axial resolution only determined by the source bandwidth. The
interferometric reference needed in OCT is replaced by computational
methods, simplifying hardware requirements. As ptychography is capable of
deconvolving the illumination contributions in the observed signal,
speckle-free images are obtained. We demonstrate the capabilities of
ptychographic optical coherence tomography (POCT) by imaging an axially
discrete lithographic structure and an axially continuous mouse brain
sample.
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