Coupling Reaction of Thioamides with Sulfonyl Azides: An Efficient Catalyst-Free Click-Type Ligation under Mild Conditions.
2014
We report a coupling reaction of thioamides and sulfonyl azides to generate sulfonyl amidines in the absence of any activation additives. The reaction progresses in various solvents under mild conditions. Water exhibits the highest performance with respect to efficiency.
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