Two members of the DUF579 family are responsible for arabinogalactan methylation in Arabidopsis

Author(s): Temple, H; Mortimer, JC; Tryfona, T; Yu, X; Lopez-Hernandez, F; Sorieul, M; Anders, N; Dupree, P | Abstract: © 2019 The Authors. Plant Direct published by American Society of Plant Biologists, Society for Experimental Biology and John Wiley a Sons Ltd. All members of the DUF579 family characterized so far have been described to affect the integrity of the hemicellulosic cell wall component xylan: GXMs are glucuronoxylan methyltransferases catalyzing 4-O–methylation of glucuronic acid on xylan; IRX15 and IRX15L, although their enzymatic activity is unknown, are required for xylan biosynthesis and/or xylan deposition. Here we show that the DUF579 family members, AGM1 and AGM2, are required for 4-O–methylation of glucuronic acid of a different plant cell wall component, the highly glycosylated arabinogalactan proteins (AGPs).