Quinoline and quinazoline compound and pharmaceutical composition thereof, and applications of quinoline and quinazoline compound and pharmaceutical composition

The present invention discloses a quinoline and quinazoline compound represented by a general formula I, pharmaceutically acceptable salts, oxynitrides and solvates thereof, and stereoisomers containing mixtures comprising various proportions of the compound, wherein R1, R2, R3, R4, RA, RB, Z1, Z2, X1, X2, X3, D, L, A ring, B ring, m and n are defined in the specification. The present invention further relates to a preparation method of the compounds, and uses of the compound, the pharmaceutically acceptable salts, the oxynitrides and the solvates thereof, and the stereoisomers containing the mixtures comprising various proportions of the compound, particularly to uses in preparation of drugs for prevention, treatment, therapy or alleviation of cancers.