A method of operating an internal combustion engine, in particular of a vehicle

The invention relates to a method for operating a a plurality of in respective cylinders (14) movably captured piston (16) having the internal combustion engine (10), wherein the internal combustion engine (10) after a stoppage it is started by injecting fuel in at least one of the cylinders (14) is introduced, wherein the resulting at least during a time preceding the standstill and of a deactivation of the internal combustion engine (10) discharge operation of the internal combustion engine, respective pressures in the cylinders (14) are detected by means of respective combustion chamber pressure sensors (26) (10), wherein at least during of the discharge operation, a setting device (28) is operated in response to the sensed pressures to adjust by means of the adjusting device (28) have respective fillings of the cylinder (14), whereby the respective piston (16) in the respective cylinders (14) for starting internal combustion engine (10) positio ned.