DNA-Encoding Enzymatically Active HIV-1 Reverse Transcriptase, but Not the Inactive Mutant, Confers Resistance to Experimental HIV-1 Challenge

Maria G. Isaguliants,Natalia N. Petrakova,Bartek Zuber,Katja Pokrovskaya,Rinat Gizatullin,Dmitrii A. Kostyuk,Anne Kjerrström,Gösta Winberg,Sergey N. Kochetkov,Jorma Hinkula,Britta Wahren

DNA-Encoding Enzymatically Active HIV-1 Reverse Transcriptase, but Not the Inactive Mutant, Confers Resistance to Experimental HIV-1 Challenge

2000

Maria G. Isaguliants
Natalia N. Petrakova
Bartek Zuber
Katja Pokrovskaya
Rinat Gizatullin
Dmitrii A. Kostyuk
Anne Kjerrström
Gösta Winberg
Sergey N. Kochetkov
Jorma Hinkula
Britta Wahren

The present study was undertaken to examine the immunogenicity of a single plasmid DNA representing the reverse transcriptase (RT) of HIV-1. Plasmids containing the enzymatically active RT as well as

Keywords:

Plasmid
Immunogenicity
Molecular biology
DNA
DNA vaccination
Virology
Mutant
Nucleotide
Reverse transcriptase
Biology
human immunodeficiency virus
dna encoding
plasmid dna

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