Structurally Redesigned Bioorthogonal Reagents for Mitochondria-Specific Prodrug Activation

Rastislav Dzijak,Juraj Galeta,Arcadio Vázquez,Jaroslav Kozák,Marika Matousova,Helena Fulka,Martin Dračínský,Milan Vrabel

Structurally Redesigned Bioorthogonal Reagents for Mitochondria-Specific Prodrug Activation

2020

Rastislav Dzijak
Juraj Galeta
Arcadio Vázquez
Jaroslav Kozák
Marika Matousova
Helena Fulka
Martin Dračínský
Milan Vrabel

The development of abiotic chemical reactions that can be performed in an organelle-specific manner can provide new opportunities in drug delivery and cell and chemical biology. However, due to the...

Keywords:

Abiotic component
Reagent
Bioorthogonal chemistry
Drug delivery
Cell
Prodrug
Chemical biology
Chemical reaction
Biochemistry
Chemistry

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