Genotoxicity of Engineered Nanomaterials Found in the Human Environment

Abstract Engineered nanomaterials are unique in our modern industrial world; however, limited information is currently available regarding exposure and hazard information, including the genotoxicity of such materials. Much work remains to be done for developing, validating, and harmonizing a tool chest for the genotoxicity of nanomaterials. Gaps remain in our understanding of potential mechanisms of the genotoxicity of nanomaterials. Until more appropriate tests are available for testing of engineered nanomaterials, the potential impact of engineered nanomaterials may continue to be underestimated without proper consideration of the genotoxicity potential of such materials. Clearly, resources need to be devoted to better approaches to the hazard identification of nanomaterials to insure safe development and application of nanotechnology, and for the protection of human health and the environment.