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Claude H. T. Chan

University of Southampton

30

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1673

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Domain Binding and Isotype Dictate the Activity of Anti-human OX40 Antibodies

2020 bioRxiv
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Investigating the underlying mechanisms of action of targeted radionuclide therapy in EGFR overexpressing solid tumours.

2019
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Abstract B055: Augmentation of OX40-dependent NK mediated antitumor activity is dependent on antibody cross-linking

2016 Cancer immunology research
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Anti-CD27 Enhances Lymphoma Immunotherapy through Profound Myeloid Cell Recruitment

2016 Blood
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Activatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domain.

2015 Journal of Biological Chemistry
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PO-0939: Surface EGFR levels rather than intrinsic radiosensitivity predict response to In-DTPA-hEGF in solid cancers

2014 Radiotherapy and Oncology
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subgroups in peripheral T-cell lymphoma Gene expression signatures delineate biological and prognostic

2014
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Inhibitory FcγRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity

2014 Blood
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Abstract LB-142: A trial of agonistic anti-CD40 antibody: Biological effects in a Cancer Research UK phase I study.

2013 Cancer Research
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This information is current as Consumption and Receptor Internalization Limited by Monoclonal Antibody Receptor IIB (CD32b) in the Mouse Is γ Immunotherapy Targeting Inhibitory Fc

2013
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