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Jesse D. Vargas

University of California, Los Angeles

14

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940

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A p97/valosin-containing protein inhibitor drug CB-5083 has a potent but reversible off-target effect on phosphodiesterase-6.

2021 Journal of Pharmacology and Experimental Therapeutics
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Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor

2021 Science Translational Medicine
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CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity

2019 ACS Chemical Biology
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Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant

2017 Proceedings of the National Academy of Sciences of the United States of America
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Signaling via the NFκB system

2016 Wiley Interdisciplinary Reviews: Systems Biology and Medicine
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Signaling via the NF kappa B system

2016
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Signaling via the NF kappa B system - eScholarship

2016
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Citations (163)
Limited specificity of IRF3 and ISGF3 in the transcriptional innate-immune response to double-stranded RNA

2015 Journal of Leukocyte Biology
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A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide

2015 Molecular Systems Biology
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Network dynamics determine the autocrine and paracrine signaling functions of TNF

2014 Genes & Development
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Citations (61)