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Thomas Brian Hamilton Mcmurry

University College Dublin

9

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136

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O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts.

2005 British Journal of Cancer
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O6-alkylguanine-DNA alkyltransferase inactivation in cancer chemotherapy.

2003 Mini-reviews in Medicinal Chemistry
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O6- -guanine is an effective inactivator of O6-alkylguanine-DNA alkyltransferase , and improves the therapeutic index of tempzolomide to a greater extent than O6 benzylguanine

1999
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Inactivation of O6-alkylguanine-DNA alkyltransferase. 1. Novel O6-(hetarylmethyl)guanines having basic rings in the side chain.

1998 Journal of Medicinal Chemistry
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MODULATING NITROSOUREA RESPONSE IN TUMORS AND NORMAL TISSUE : APPLICATION TO FOTEMUSTINE

1996 Medicamentos de actualidad
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Derives de la pyrimidine et derives de la guanine, et leur utilisation pour traiter des cellules tumorales

1996
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Guanine derivatives 06-substituted, a process for their preparation and their use in treating tumor cells.

1994
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O6-substituted guaninederivate, proceed to their production and their application for treatment of tumor cells

1994
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Nucleoside analogues. XI, The acylation of N-(ω-aminoalkyl)uracils and a bicyclic isomer

1991 Journal of Chemical Research-s
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