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Yi Shen

Uniformed Services University of the Health Sciences

10

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4-1BB (CD137) differentially regulates murine in vivo protein- and polysaccharide-specific immunoglobulin isotype responses to Streptococcus pneumoniae.

2003 Infection and Immunity
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Dendritic Cells Pulsed with Intact Streptococcus pneumoniae Elicit both Protein- and Polysaccharide-specific Immunoglobulin Isotype Responses In Vivo through Distinct Mechanisms

2002 Journal of Experimental Medicine
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The Mechanism Underlying T Cell Help for Induction of an Antigen-Specific In Vivo Humoral Immune Response to Intact Streptococcus pneumoniae Is Dependent on the Type of Antigen

2002 Journal of Immunology
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Endogenous Pro- and Anti-Inflammatory Cytokines Differentially Regulate an In Vivo Humoral Response to Streptococcus pneumoniae

2002 Infection and Immunity
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deliver help for both polysaccharide- and protein-specific Ig responses. However, these responses differ fundamentally in their mechanism of action.

2001
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Distinct Types of T-cell Help for the Induction of a Humoral Immune Response to Streptococcus pneumoniae

2001 Trends in Immunology
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NF-κB/p50 and NF-κB/c-Rel differentially regulate the activity of the 3′αE-hsl,2 enhancer in normal murine B cells in an activation-dependent manner

2000 International Immunology
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B7 requirements for primary and secondary protein- and polysaccharide-specific Ig isotype responses to Streptococcus pneumoniae.

2000 Journal of Immunology
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In Vivo Polysaccharide-Specific IgG Isotype Responses to Intact Streptococcus pneumoniae Are T Cell Dependent and Require CD40- and B7-Ligand Interactions

1999 Journal of Immunology
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The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3.

1999 Journal of Immunology
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