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Edward H. Schuchman

Icahn School of Medicine at Mount Sinai

334

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15815

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SiO2 stimulates macrophage stress to induce the transformation of lung fibroblasts into myofibroblasts and its relationship with the sphingomyelin metabolic pathway

2021 Journal of Applied Toxicology
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Acid Ceramidase Protects Against Hepatic Ischemia/Reperfusion Injury by Modulating Sphingolipid Metabolism and Reducing Inflammation and Oxidative Stress

2021 Frontiers in Cell and Developmental Biology
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New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy.

2021 Orphanet Journal of Rare Diseases
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Table 1. [Molecular Genetic Testing Used in Acid Sphingomyelinase Deficiency].

2021
- Melissa P. Wasserstein
- Edward H. Schuchman
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Modulation of the endocannabinoid receptor CB2 as a novel treatment for the lysosomal diseases

2021 Molecular Genetics and Metabolism
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A New Fluorescent Method to Detect Sulfamidase Activity in Blood, Tissue Extracts and Dried Blood Spots

2021
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The incidence of acid sphingomyelinase deficiency (ASMD) in cases of suspected Gaucher disease, genotype-phenotype correlation together with Lyso-SPM biomarker

2021 Molecular Genetics and Metabolism
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Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes.

2021 Molecular metabolism
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Growth Plate Pathology in the Mucopolysaccharidosis Type VI Rat Model-An Experimental and Computational Approach.

2020
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Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling.

2020 Embo Molecular Medicine
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