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Thomas Leiser
Thomas Leiser
Natural product
Biochemistry
Chemistry
Histone deacetylase
HDAC1
5
Papers
138
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Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A.
2013
ChemMedChem
Matthias G. J. Baud
Patricia Haus
Thomas Leiser
Franz-Josef Meyer-Almes
Matthew J. Fuchter
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Citations (17)
Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors
2013
Beilstein Journal of Organic Chemistry
Matthias G. J. Baud
Thomas Leiser
Vanessa Petrucci
Mekala Gunaratnam
Stephen Neidle
Franz-Josef Meyer-Almes
Matthew J. Fuchter
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Citations (20)
Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets.
2012
Journal of Medicinal Chemistry
Matthias G. J. Baud
Thomas Leiser
Patricia Haus
Sharon Samlal
Ai Ching Wong
Robert J. Wood
Vanessa Petrucci
Mekala Gunaratnam
Siobhan M. Hughes
Lakjaya Buluwela
Fabrice Turlais
Stephen Neidle
Franz-Josef Meyer-Almes
Andrew J. P. White
Matthew J. Fuchter
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Citations (74)
New synthetic strategies towards psammaplin A, access to natural product analogues for biological evaluation
2011
Organic and Biomolecular Chemistry
Matthias G. J. Baud
Thomas Leiser
Franz-Josef Meyer-Almes
Matthew J. Fuchter
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Citations (27)
Abstract B166: Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets.
2011
Molecular Cancer Therapeutics
Matthew J. Fuchter
Matthias G. J. Baud
Thomas Leiser
Sharon Samlal
Ai Ching Wong
Robert J. Wood
Mekala Gunaratnam
Siobhan M. Hughes
Lakjaya Buluwela
Fabrice Turlais
Stephen Neidle
Franz-Josef Meyer-Almes
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