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Laura H. Jacobson

Novartis
Florey Institute of Neuroscience and Mental Health
University of Melbourne

82

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Manipulation of REM sleep via orexin and GABAA receptor modulators differentially affects fear extinction in mice: effect of stable versus disrupted circadian rhythm.

2021 Sleep
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Decreased Orexin Receptor 1 mRNA Expression in the Locus Coeruleus in Both Tau Transgenic rTg4510 and Tau Knockout Mice and Accompanying Ascending Arousal System Tau Invasion in rTg4510.

2021 Journal of Alzheimer's Disease
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Development of a LC-ESI-MRM method for the absolute quantification of orexin A in the CSF of individual mice

2021
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Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360.

2021 Journal of Medicinal Chemistry
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Discovery of Umibecestat (CNP520): A Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer's Disease.

2021 Journal of Medicinal Chemistry
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Circadian disruption impairs fear extinction and memory of conditioned safety in mice

2020 Behavioural Brain Research
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Reward Motivation and Cognitive Flexibility in Tau Null-Mutation Mice

2020 Neurobiology of Aging
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Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy.

2020 Journal of Neuroinflammation
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Effects of orexin receptor antagonism on human sleep architecture: A systematic review

2020 Sleep Medicine Reviews
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Novel alterations to the corneal neuroimmune phenotype in mice with central nervous system tauopathy

2019 Investigative Ophthalmology & Visual Science
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