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Ira Pastan

Laboratory of Molecular Biology
National Institutes of Health

1372

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102589

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Phase 1 trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox combined with rituximab for relapsed/refractory hairy cell leukemia

2021 Journal of Clinical Oncology
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Phase I study of mesothelin-targeted immunotoxin LMB-100 in combination with tofacitinib in persons with pancreatobiliary cancer or other mesothelin expressing solid tumors.

2021 Journal of Clinical Oncology
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Indirect podocyte injury manifested in a partial podocytectomy mouse model

2021 American Journal of Physiology-renal Physiology
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Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial.

2021 Journal of Hematology & Oncology
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Phase I study of mesothelin-targeted immunotoxin LMB-100 in combination with tofacitinib in patients with advanced pancreatobiliary cancer.

2021 Journal of Clinical Oncology
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Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis.

2021 Proceedings of the National Academy of Sciences of the United States of America
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Moxetumomab pasudotox as re-treatment for heavily-pretreated relapsed hairy cell leukemia.

2021 Leukemia & Lymphoma
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Development of Recombinant Immunotoxins for Hairy Cell Leukemia.

2020
- Robert J. Kreitman
- Ira Pastan
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Mechanisms of Resistance to Immunotoxins Containing Pseudomonas Exotoxin A in Cancer Therapy.

2020
- Michael Dieffenbach
- Ira Pastan
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Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine

2020
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