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Charles B. Shoemaker

Tufts University
Harvard University
AgResearch

160

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Delivery of single-domain antibodies into neurons using a chimeric toxin-based platform is therapeutic in mouse models of botulism.

2021 Science Translational Medicine
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Identification and characterization of a new 34 kDa MORN motif-containing sporozoite surface-exposed protein, Cp-P34, unique to Cryptosporidium.

2021 International Journal for Parasitology
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A heterohexameric protein consisting of six linked single-domain antibodies is highly protective for BoNT/A, BoNT/B and BoNT/E exposures

2021 bioRxiv
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Neuronal delivery of antibodies has therapeutic effects in animal models of botulism.

2021 Science Translational Medicine
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Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

2021 bioRxiv
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Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody.

2021 Journal of Controlled Release
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Delivery of single-domain antibodies into neurons using a chimeric, toxin-based platform cures botulism in mouse models

2021 Toxicon
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Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells.

2020 Toxins
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Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function

2020 Toxins
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Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins

2020 Cell Reports
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