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Joy A. Nishime

United States Military Academy

9

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ROUTE-DEPENDENT NONLINEAR PHARMACOKINETICS OF A NOVEL HIV PROTEASE INHIBITOR: INVOLVEMENT OF ENZYME INACTIVATION

2000 Drug Metabolism and Disposition
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Influence of P-Glycoprotein on the Transport and Metabolism of Indinavir in Caco-2 Cells Expressing Cytochrome P-450 3A4

2000 Journal of Pharmacology and Experimental Therapeutics
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Modulation of Rat Cytochrome P-450 by an Investigational HIV Protease Inhibitor

1999 Drug Metabolism and Disposition
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Effect of Dexamethasone on the Intestinal First-Pass Metabolism of Indinavir in Rats: Evidence of Cytochrome P-450 A and p-Glycoprotein Induction

1999 Drug Metabolism and Disposition
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Metabolite–P450 Complex Formation by Methylenedioxyphenyl HIV Protease Inhibitors in Rat and Human Liver Microsomes

1998 Biochemical Pharmacology
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Hepatic Microsomal Metabolism of Montelukast, a Potent Leukotriene D4 Receptor Antagonist, in Humans

1997 Drug Metabolism and Disposition
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Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.

1996 Drug Metabolism and Disposition
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Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor.

1995 Journal of Pharmacology and Experimental Therapeutics
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Time- and dose-dependent pharmacokinetics of L-754,394, an HIV protease inhibitor, in rats, dogs and monkeys.

1995 Journal of Pharmacology and Experimental Therapeutics
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Citations (24)