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Yi Zheng

Cincinnati Children's Hospital Medical Center
Hospital Research Foundation
University of Cincinnati

453

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19636

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Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia.

2021 Cell Stem Cell
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Modulation of both intrinsic and extrinsic factors additively promotes rewiring of corticospinal circuits after spinal cord injury.

2021 The Journal of Neuroscience
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Structure-Activity Relationship Analysis of Analogs of Rhosin, a RhoA Inhibitor, Reveals a New Generation of Improved Antiplatelet Agents

2021 Blood
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Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis.

2021 Scientific Reports
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An aged bone marrow niche restrains rejuvenated hematopoietic stem cells.

2021 Stem Cells
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Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.

2021 EMBO Reports
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Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia.

2021 Leukemia
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Abstract LB198: Inhibition of the RAC Activator VAV3 by the small molecule IODVA1 impedes RAC signaling & overcomes resistance to tyrosine kinase inhibition in lymphoblastic leukemia

2021 Cancer Research
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Structure of an inactive conformation of GTP-bound RhoA GTPase.

2021 Structure
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Chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability.

2021 Blood
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