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Eiki Tanabe
Eiki Tanabe
Astellas Pharma
Biochemistry
Fragment-based lead discovery
Chemistry
Stereochemistry
Spermidine synthase
4
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60
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An NMR Biochemical Assay for Fragment-Based Drug Discovery: Evaluation of an Inhibitor Activity on Spermidine Synthase of Trypanosoma cruzi
2016
Journal of Medicinal Chemistry
Kazuhiko Yamasaki
Osamu Tani
Yukihiro Tateishi
Eiki Tanabe
Ichiji Namatame
Tatsuya Niimi
Koji Furukawa
Hitoshi Sakashita
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Citations (7)
Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening
2015
Bioorganic & Medicinal Chemistry
Yasushi Amano
Eiki Tanabe
Tomohiko Yamaguchi
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Citations (11)
Structural insights into the novel inhibition mechanism of Trypanosoma cruzi spermidine synthase
2015
Acta Crystallographica Section D-biological Crystallography
Yasushi Amano
Ichiji Namatame
Yukihiro Tateishi
Kazuya Honboh
Eiki Tanabe
Tatsuya Niimi
Hitoshi Sakashita
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Citations (16)
Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography
2014
Bioorganic & Medicinal Chemistry
Yasushi Amano
Tomohiko Yamaguchi
Eiki Tanabe
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Citations (26)
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