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Jonathan A. Javitch

Columbia University

335

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20648

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Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.

2021 Science Advances
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A novel luminescence-based-β-arrestin recruitment assay for unmodified receptors

2021 Journal of Biological Chemistry
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Single-molecule FRET imaging of GPCR dimers in living cells.

2021 Nature Methods
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Tuning the Baird Aromatic Triplet State Energy of Cyclooctatetraene to Maximize the Self-Healing Mechanism in Organic Fluorophores

2021 Biophysical Journal
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The Role of the Dopamine Transporter in the Effects of Amphetamine on Sleep and Sleep Architecture in Drosophila.

2021 Neurochemical Research
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Delineating the interactions between the cannabinoid CB2 receptor and its regulatory effectors; β-arrestins and G protein-coupled receptor kinases

2021 British Journal of Pharmacology
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Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels.

2021 iScience
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Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.

2021 Journal of Biological Chemistry
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Site selective C-H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy.

2021 Nature Communications
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A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects.

2021 Journal of Medicinal Chemistry
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