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Jay Ezhuthachan
Jay Ezhuthachan
AstraZeneca
Kinase
Biochemistry
Chemistry
Enzyme inhibitor
Hit to lead
3
Papers
28
Citations
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Discovery of a novel class of triazolones as checkpoint kinase inhibitors--hit to lead exploration.
2010
Bioorganic & Medicinal Chemistry Letters
Vibha Oza
Susan Ashwell
Patrick Brassil
Jason Breed
Chun Deng
Jay Ezhuthachan
Heather Haye
Candice Horn
James W. Janetka
Paul Lyne
Nicholas John Newcombe
Ludo Otterbien
Martin Pass
Jon Read
Sian Roswell
Mei Su
Dorin Toader
Dingwei Yu
Yan Yu
Anna Valentine
Peter J. H. Webborn
Ann White
Sonya Zabludoff
Xiaolan Zheng
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Citations (13)
Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors-Hit to Lead Exploration.
2010
Bioorganic & Medicinal Chemistry
Özã
Susan Ashwell
Patrick Brassil
Jason Breed
Chun Deng
Jay Ezhuthachan
Heather Haye
Candice Horn
James W. Janetka
Paul Lyne
Nicholas John Newcombe
L Otterbien
Martin Pass
Jon Read
S Roswell
Mei Su
Dorin Toader
Dingwei Yu
Yan Yu
Anna Valentine
Peter J. H. Webborn
Anne White
Sonya Zabludoff
Xiaolan Zheng
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Citations (7)
Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity.
2009
Bioorganic & Medicinal Chemistry Letters
Paul Lyne
Brian Aquila
Donald J. Cook
Les A. Dakin
Jay Ezhuthachan
Stephanos Ioannidis
Timothy Pontz
Mei Su
Qing Ye
Xiaolan Zheng
Michael Howard Block
Scott Cowen
Tracy L. Deegan
John W. Lee
David Scott
Dominique Custeau
Lisa Drew
Srinivasu Poondru
Minhui Shen
Allan Wu
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Citations (8)
1