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Sheela Ashok
Sheela Ashok
Biochemistry
Stereochemistry
Chemistry
Acetylation
Cofactor
3
Papers
203
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Structural Basis for (S)-3,4-Dicarboxyphenylglycine (DCPG) As a Potent and Subtype Selective Agonist of the mGlu8 Receptor
2018
Journal of Medicinal Chemistry
Qi Chen
Joseph D. Ho
Sheela Ashok
Michelle C. Vargas
Jing Wang
S. Atwell
Mark G. Bures
Jeffery M. Schkeryantz
James A. Monn
Junliang Hao
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Citations (4)
Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain.
2013
PLOS ONE
Stephen Antonysamy
Bradley Condon
Zhanna Druzina
J.B. Bonanno
T. Gheyi
Feiyu Zhang
Iain MacEwan
Aiping Zhang
Sheela Ashok
L. Rodgers
Marijane Russell
John G. Luz
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Citations (68)
The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition.
2013
Journal of Medicinal Chemistry
Xun Zhao
Dagart Allison
Bradley Condon
Feiyu Zhang
T. Gheyi
Aiping Zhang
Sheela Ashok
Marijane Russell
Iain MacEwan
Yuewei Qian
James A. Jamison
John G. Luz
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Citations (131)
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