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Vincent Roh

Peter MacCallum Cancer Centre

3

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Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice

2014 Biochemical Journal
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An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.

2012 Journal of Clinical Investigation
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Physiological Levels of Pik3caH1047R Mutation in the Mouse Mammary Gland Results in Ductal Hyperplasia and Formation of ERα-Positive Tumors

2012 PLOS ONE
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Citations (49)