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Douglas R Smith
Douglas R Smith
GlaxoSmithKline
Chemistry
5-HT receptor
5-HT6 receptor
Receptor
Chemical synthesis
4
Papers
337
Citations
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SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models
2006
European Journal of Pharmacology
Warren D. Hirst
Tania O. Stean
Derek Rogers
David Sunter
Pippa Pugh
Stephen Frederik SmithKline Beecham Phar Moss
Steven Mark Bromidge
Graham J. Riley
Douglas R Smith
Sarah Bartlett
Christian Heidbreder
Alan R. Atkins
Laurent P. Lacroix
Lee A. Dawson
Andrew G. Foley
Ciaran M. Regan
Neil Upton
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Citations (202)
Pharmacological profile of SB-357134: a potent, selective, brain penetrant, and orally active 5-HT6 receptor antagonist
2002
Pharmacology, Biochemistry and Behavior
Tania O. Stean
Warren D. Hirst
David R. Thomas
Gary W. Price
Derek Rogers
Graham J. Riley
Steven Mark Bromidge
Halina T Serafinowska
Douglas R Smith
Sarah Bartlett
Nigel J. Deeks
Mark S. Duxon
Neil Upton
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Citations (60)
Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists.
2002
Bioorganic & Medicinal Chemistry Letters
Steven Mark Bromidge
Stephen E. Clarke
Frank D. King
Peter J. Lovell
Helen Newman
Graham J. Riley
Carol Routledge
Halina T Serafinowska
Douglas R Smith
David R. Thomas
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Citations (17)
Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)
2001
Bioorganic & Medicinal Chemistry Letters
Steven Mark Bromidge
Stephen E. Clarke
Tracey Gager
Kerry Griffith
Phillip Jeffrey
Andrew Jennings
Graham F. Joiner
Frank King
Peter J. Lovell
S Moss
Helen Newman
Graham J. Riley
Derek Rogers
Carol Routledge
Halina T. Serafinowska
Douglas R Smith
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Citations (58)
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