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Patrick Ball
Patrick Ball
Bangor University
Enzyme
Prodrug
Biochemistry
Nitroreductase
Chemistry
4
Papers
20
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Evaluation of two xenobiotic reductases from Pseudomonas putida for their suitability for magnetic nanoparticle-directed enzyme prodrug therapy as a novel approach to cancer treatment.
2020
Patrick Ball
Jennifer Halliwell
Simon Anderson
Vanessa V. Gwenin
Christopher Gwenin
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Citations (2)
Time dependent HPLC analysis of the product ratio of enzymatically reduced prodrug CB1954 by a modified and immobilised nitroreductase
2019
European Journal of Pharmaceutical Sciences
Patrick Ball
Emma Thompson
Simon Anderson
Vanessa Valerie Gwenin
Christopher Gwenin
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Citations (6)
Cell-Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug Therapy
2019
Journal of Functional Biomaterials
Simon D. Anderson
Robert J. Hobbs
Vanessa V. Gwenin
Patrick Ball
Lindsey Bennie
Jonathan A. Coulter
Christopher Gwenin
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Citations (3)
Identification of novel nitroreductases from Bacillus cereus and their interaction with the CB1954 prodrug.
2015
Biochemical Pharmacology
Vanessa Valerie Gwenin
Paramasivan Poornima
Jennifer Halliwell
Patrick Ball
George Robinson
Christopher Gwenin
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Citations (9)
1