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Joseph Chen
Joseph Chen
Schering-Plough
Amyloid precursor protein secretase
In vivo
Amyloid precursor protein
Pharmacology
γ secretase
3
Papers
71
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In Vivo Characterization of a Novel γ-Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects
2013
International Journal of Alzheimer's Disease
Lynn Hyde
Qi Zhang
Robert A. Del Vecchio
Prescott T. Leach
Mary Cohen-Williams
Lei Chen
Gwendolyn T. Wong
Nansie A. McHugh
Joseph Chen
Guy A. Higgins
Theodros Asberom
Wei Li
Dmitri A. Pissarnitski
Diane Levitan
Amin A. Nomeir
John W. Clader
Lili Zhang
Eric M. Parker
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Citations (4)
Studies to Investigate the in Vivo Therapeutic Window of the γ-Secretase Inhibitor N2-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-l-alaninamide (LY411,575) in the CRND8 Mouse
2006
Journal of Pharmacology and Experimental Therapeutics
Lynn A. Hyde
Nansie A. McHugh
Joseph Chen
Qi Zhang
Denise Manfra
Amin A. Nomeir
Hubert B. Josien
Thomas A. Bara
John W. Clader
Lili Zhang
Eric M. Parker
Guy A. Higgins
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Citations (67)
P4-364 Rapid in-vivo assessment of therapeutic window of two γ-secretase inhibitors in transgenic CRND8 mice
2004
Neurobiology of Aging
Lynn A. Hyde
Denise Manfra
Nansie A. McHugh
Qi Zhang
Laura W. Engstrom
Maria Pinzon-Ortiz
Joseph Chen
Hubert Josien
John W. Clader
Lili Zhang
Eric M. Parker
Guy A. Higgins
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