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Thomas A. Milne

University of Oxford
Rockefeller University

94

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8769

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A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

2021 Nature Communications
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A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells

2021 bioRxiv
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A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.

2021 Genome Research
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Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro

2021 Molecules
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Defining genome architecture at base-pair resolution

2021 Nature
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Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation.

2021 Cell Reports
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A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo

2021 Journal of Medicinal Chemistry
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Repressed Chromatin Drives Leukaemogenesis in Mutant IDH2 Acute Myeloid Leukaemia Via Inhibition of Granulocyte Differentiation and Cell Cycle Progression

2021 Blood
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Pharmacological Induction of NOXA Sensitizes High-Risk B Cell Acute Lymphoblastic Leukemia Cells to Venetoclax

2020 Blood
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A phenotypic screen identifies a compound series that induces differentiation of acute myeloid leukemia cells in vitro and shows anti-tumour effects in vivo

2020 bioRxiv
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