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Christine A. Pratilas
Christine A. Pratilas
Memorial Sloan Kettering Cancer Center
Mitogen-activated protein kinase kinase
MAPK/ERK pathway
Cancer research
Kinase
Protein kinase A
2
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1613
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0.02
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V600EBRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway
2009
Proceedings of the National Academy of Sciences of the United States of America
Christine A. Pratilas
Barry S. Taylor
Qing Ye
Agnes Viale
Chris Sander
David B. Solit
Neal Rosen
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Citations (438)
BRAF mutation predicts sensitivity to MEK inhibition
2006
Nature
David B. Solit
Levi A. Garraway
Christine A. Pratilas
Ayana Sawai
Gad Getz
Andrea Basso
Qing Ye
Jose Lobo
Yuhong She
Iman Osman
Todd R. Golub
Judith Sebolt-Leopold
William R. Sellers
Neal Rosen
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Citations (1175)
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