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Patricia Linley
Patricia Linley
Harbor Branch Oceanographic Institute
Biochemistry
Cytotoxicity
Sponge
Cell culture
In vitro
5
Papers
254
Citations
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Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
2016
International Journal of Cancer
Esther A. Guzmán
Qunli Xu
Tara P. Pitts
Kaoru Mitsuhashi
Cheryl H. Baker
Patricia Linley
Judy Oestreicher
Karen TenDyke
Priscilla L. Winder
Edward M. Suh
Amy E. Wright
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Citations (23)
A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis
2011
Investigational New Drugs
Esther A. Guzmán
Jacob D. Johnson
Patricia Linley
Sarath Gunasekera
Amy E. Wright
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Citations (39)
Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima.
2011
Bioorganic & Medicinal Chemistry
Priscilla L. Winder
Heather L. Baker
Patricia Linley
Esther A. Guzmán
Shirley A. Pomponi
M. Cristina Díaz
John K. Reed
Amy E. Wright
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Citations (16)
Isolation, synthesis, and biological activity of aphrocallistin, an adenine-substituted bromotyramine metabolite from the Hexactinellida sponge Aphrocallistes beatrix.
2009
Journal of Natural Products
Amy E. Wright
Gregory P. Roth
Jennifer K. Hoffman
Daniela Divlianska
Diana Pechter
Susan H. Sennett
Esther A. Guzmán
Patricia Linley
Peter J. McCarthy
Tara P. Pitts
Shirley A. Pomponi
John K. Reed
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Citations (18)
Neopeltolide, a Macrolide from a Lithistid Sponge of the Family Neopeltidae⊥
2007
Journal of Natural Products
Amy E. Wright
Julianne Cook Botelho
Esther A. Guzmán
Dedra Harmody
Patricia Linley
Peter J. McCarthy
Tara P. Pitts
Shirley A. Pomponi
John K. Reed
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Citations (158)
1