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Jordan Tang

Oklahoma Medical Research Foundation
University of Oklahoma Health Sciences Center
University of Oklahoma

199

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Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies

2019 ChemMedChem
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Cardosin A endocytosis mediated by integrin leads to lysosome leakage and apoptosis of epithelial cells

2019 Proteins
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Cover Feature: Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies (ChemMedChem 5/2019)

2019 ChemMedChem
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Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand

2018 Bioorganic & Medicinal Chemistry Letters
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Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1'-P2' ligands.

2017 Bioorganic & Medicinal Chemistry Letters
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Co-crystal of BACE1 with compound 0211

2016
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Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes

2016 Chemical Science
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Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand

2015 Bioorganic & Medicinal Chemistry Letters
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Prospects of β-Secretase Inhibitors for the Treatment of Alzheimer’s Disease

2015 ChemMedChem
- Arun K. Ghosh
- Jordan Tang
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Beneficial Effects of the β-Secretase Inhibitor GRL-8234 in 5XFAD Alzheimer’s Transgenic Mice Lessen During Disease Progression

2015 Current Alzheimer Research
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