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Trudy H. Grossman

ARIAD Pharmaceuticals, Inc.

11

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Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.

2006 Chemical Biology & Drug Design
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Multiple inhibitor analysis of the brequinar and leflunomide binding sites on human dihydroorotate dehydrogenase.

2001 Biochemistry
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Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

2000 Applied and Environmental Microbiology
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Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

2000 Structure
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Production of secreted, soluble human two-domain CD4 protein in Escherichia coli

1999 Journal of Immunological Methods
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Expression and characterization of E. coli-produced soluble, functional human dihydroorotate dehydrogenase: a potential target for immunosuppression.

1999 Journal of Molecular Microbiology and Biotechnology
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An Expression Vector Encoding a lacZ Reporter Gene Facilitates Identification of Stable, High-Producing CHO Cell Clones

1997 Plasmid
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