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Frank Verheggen

Center for Global Development

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Darexaban (YM150), an oral direct factor Xa inhibitor, has no effect on the pharmacokinetics of digoxin

2014 European Journal of Drug Metabolism and Pharmacokinetics
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Clinical pharmacokinetics, pharmacodynamics, safety and tolerability of darexaban, an oral direct factor Xa inhibitor, in healthy Caucasian and Japanese subjects

2013 Biopharmaceutics & Drug Disposition
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Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans

2013 Xenobiotica
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YM150, An Oral Direct Inhibitor of Factor Xa, Demonstrated a Predictable and Dose-Proportional Pharmacokinetic/Pharmacodynamic Profile After Single and Multiple Dosing: Results From Three Studies

2010 Blood
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