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James Chadwick
James Chadwick
University of Leeds
Enzyme
Biochemistry
Chemistry
Cellular Assay
Ligand (biochemistry)
3
Papers
41
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Discovery of biphenylacetamide-derived inhibitors of BACE1 using de novo structure-based molecular design.
2013
Journal of Medicinal Chemistry
N. Yi Mok
James Chadwick
Katherine A. B. Kellett
Eva Casas-Arce
Nigel M. Hooper
A. Peter Johnson
Colin W. G. Fishwick
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Citations (16)
Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening
2009
Bioorganic & Medicinal Chemistry Letters
N. Yi Mok
James Chadwick
Katherine A.B. Kellett
Nigel M. Hooper
A. Peter Johnson
Colin W. G. Fishwick
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Citations (25)
P2-482: De novo design of cellular active beta-secretase inhibitors
2008
Alzheimers & Dementia
Ngai Y. Mok
James Chadwick
Katherine A.B. Davey
Nigel M. Hooper
A. Peter Johnson
Colin W. G. Fishwick
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1