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Pierre-Yves Jean-Charles

Duke University

18

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382

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The deubiquitinase ubiquitin specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling

2019 Journal of Biological Chemistry
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Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9

2018 Science Signaling
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USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis

2018 Arteriosclerosis, Thrombosis, and Vascular Biology
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G Protein–Coupled Receptor Signaling Through β-Arrestin–Dependent Mechanisms

2017 Journal of Cardiovascular Pharmacology
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Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling

2017 JCI insight
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Chapter One - Ubiquitination and Deubiquitination of G Protein-Coupled Receptors

2016 Progress in Molecular Biology and Translational Science
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Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction.

2016 Journal of Cellular Physiology
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Chapter Nine - Cellular Roles of Beta-Arrestins as Substrates and Adaptors of Ubiquitination and Deubiquitination.

2016 Progress in Molecular Biology and Translational Science
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Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation

2016 Journal of Biological Chemistry
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Abstract 20088: Ubiquitin-Specific Protease 20 Attenuates Atherosclerosis through Activity in Smooth Muscle Cells

2016 Circulation
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