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Kyle J. Seamon
Kyle J. Seamon
Johns Hopkins University School of Medicine
Biology
Biochemistry
SAMHD1
DNA
Molecular biology
5
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191
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Inhibition of hUNG2 Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-fluorodeoxyuridine (FdU) and Raltitrexed (RTX) but not Fluorouracil (FU).
2021
Molecular Pharmacology
Eric S. Christenson
Anthony S. Gizzi
Junru Cui
Matthew Egleston
Kyle J. Seamon
Michael DePasquale
Benjamin Orris
Ben Ho Park
James T. Stivers
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SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity
2015
Nucleic Acids Research
Kyle J. Seamon
Zhiqiang Sun
Luda S. Shlyakhtenko
Yuri L. Lyubchenko
James T. Stivers
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Citations (89)
A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase
2015
Journal of Biomolecular Screening
Kyle J. Seamon
James T. Stivers
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Citations (28)
GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state
2014
Proceedings of the National Academy of Sciences of the United States of America
Erik C. Hansen
Kyle J. Seamon
Shannen L. Cravens
James T. Stivers
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Citations (73)
Faculty Opinions recommendation of Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.
2013
Douglas N. Robinson
Kyle J. Seamon
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