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Adam Tanner
Adam Tanner
Vertex Pharmaceuticals
Kinase
Biochemistry
Chemistry
Molecular biology
Biology
4
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62
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Discovery of Selective, Orally Bioavailable PyrazolopyridineInhibitors of Protein Kinase Cθ (PKCθ) That AmeliorateSymptoms of Experimental Autoimmune Encephalomyelitis
2019
ACS Medicinal Chemistry Letters
Philip N. Collier
Heather Twin
Ronald Knegtel
Dean Boyall
Guy Brenchley
Christopher John Davis
Shazia B. Keily
Chau Mak
Andrew Miller
Francoise Pierard
Luca Settimo
Clare M. Bolton
Peter Chiu
Adam Curnock
Elisabeth Doyle
Adam Tanner
Juan Miguel Jimenez
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Citations (4)
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.
2014
Acta Crystallographica Section D-biological Crystallography
Michael Kenneth Swan
Valerie Legris
Adam Tanner
Philip Michael Reaper
Sarah Vial
Rebecca Bordas
John Pollard
Peter Charlton
Julian Golec
Jay A. Bertrand
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Citations (49)
Structure-based optimization of aminopyridines as PKCθ inhibitors
2012
Bioorganic & Medicinal Chemistry Letters
Juan Miguel Jimenez
Christopher John Davis
Dean Boyall
Damien Fraysse
Ronald Knegtel
Luca Settimo
Stephen Young
Claire M. Bolton
Peter Chiu
Adam Curnock
Richele Rasmussen
Adam Tanner
Ian Ager
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Citations (9)
Inhibiteurs de la phosphatidylinositol 3-kinase
2007
Tiansheng Wang
Jeremy Green
Mark Cornebise
Brian Ledford
Jonathan D. Parsons
Adam Tanner
James Westcott
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