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Melissa T. Ogorman
Melissa T. Ogorman
Biochemistry
Enzyme inhibitor
Chemistry
Aldose reductase
Aldehyde Reductase
3
Papers
134
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A Novel Series of Non-Carboxylic Acid, Non-Hydantoin Inhibitors of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models: 6-(5-Chloro-3-methylbenzofuran-2-sulfonyl)-2H-pyridazin-3-one and Congeners
2005
Journal of Medicinal Chemistry
Banavara L. Mylari
Sandra J. Armento
David A. Beebe
Edward L. Conn
James B. Coutcher
Michael S. Dina
Melissa T. Ogorman
Michael C. Linhares
William H. Martin
Peter J. Oates
David A. Tess
Gregory J. Withbroe
William James Zembrowski
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Citations (60)
A Highly Selective, Non-Hydantoin, Non-Carboxylic Acid Inhibitor of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models: 6-(5-Chloro-3-methylbenzofuran- 2-sulfonyl)-2-H-pyridazin-3-one
2003
Journal of Medicinal Chemistry
Banavara L. Mylari
Sandra J. Armento
David A. Beebe
Edward L. Conn
James B. Coutcher
Michael S. Dina
Melissa T. Ogorman
Michael C. Linhares
William H. Martin
Peter J. Oates
David A. Tess
Gregory J. Withbroe
William James Zembrowski
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Citations (58)
A Sorbitol Dehydrogenase Inhibitor of Exceptional in Vivo Potency with a Long Duration of Action: 1-(R)-{4-[4-(4,6-Dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl}ethanol
2002
Journal of Medicinal Chemistry
Banavara L. Mylari
Peter J. Oates
William James Zembrowski
David A. Beebe
Edward L. Conn
James B. Coutcher
Melissa T. Ogorman
Michael C. Linhares
Gregory J. Withbroe
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Citations (16)
1