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Misako Okuno

RIKEN Brain Science Institute

9

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1019

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Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

2015 Human Molecular Genetics
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Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations

2011 Nucleic Acids Research
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Genetic ablation and chemical inhibition of IP3R1 reduce mutant huntingtin aggregation

2011 Biochemical and Biophysical Research Communications
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Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

2011 Molecular Cell
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Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

2010 Nature Biotechnology
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Inhibition of Rho Kinases Enhances the Degradation of Mutant Huntingtin

2009 Journal of Biological Chemistry
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Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing

2008 Journal of Cell Biology
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A new membrane microdomain-dependent regulatory mechanism of amyloid precursor protein processing

2007 Neuroscience Research
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Bax-inhibiting peptide derived from mouse and rat Ku70

2004 Biochemical and Biophysical Research Communications
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Citations (68)