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Nelleke Snelder
Nelleke Snelder
Leiden University
Internal medicine
Endocrinology
Chemistry
Cardiac output
Prazosin
5
Papers
55
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Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approach
2017
Journal of Pharmacology and Experimental Therapeutics
Nelleke Snelder
Bart A. Ploeger
Olivier Luttringer
Dean F. Rigel
Randy Lee Webb
David Louis Feldman
Fumin Fu
Michael E. Beil
Liang Jin
Donald Stanski
Meindert Danhof
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Citations (6)
Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation.
2014
Drug Metabolism and Disposition
Nelleke Snelder
Berend Arnold Ploeger
Olivier Luttringer
Donald Stanski
Meindert Danhof
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Citations (9)
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling
2014
British Journal of Pharmacology
Nelleke Snelder
Bart A. Ploeger
Olivier Luttringer
Dean F. Rigel
Fumin Fu
Michael E. Beil
Donald Stanski
Meindert Danhof
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Citations (19)
PKPD modelling of the interrelationship between mean arterial BP, cardiac output and total peripheral resistance in conscious rats
2013
British Journal of Pharmacology
Nelleke Snelder
Bart A. Ploeger
Olivier Luttringer
Dean F. Rigel
Randy Lee Webb
David Louis Feldman
Fumin Fu
Michael E. Beil
Liang Jin
Donald Stanski
Meindert Danhof
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Citations (21)
RESEARCH PAPER Estimation of binding rate constants using a simultaneous mixed-effects method: application to monoamine transporter reuptake inhibitor reboxetine
2010
Neil Benson
Nelleke Snelder
Bart A. Ploeger
Carolyn Napier
Harriet Sale
N. J. M. Birdsall
Piet H. van der Graaf
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