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B. Lang
B. Lang
Boehringer Ingelheim
Generalized pustular psoriasis
Downregulation and upregulation
Immunology
Receptor antibody
Biology
2
Papers
1
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0
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049 Generalized pustular psoriasis (GPP) and palmoplantar pustulosis (PPP) both show upregulation of the IL-36, neutrophil chemokine, and innate pathways that are modulated by spesolimab, an anti-IL-36 receptor antibody, treatment
2020
Journal of Investigative Dermatology
Patrick Baum
Sudha Visvanathan
Sandra Garcet
J. Roy
Ramona Schmid
S. Bossert
B. Lang
Hervé Bachelez
Robert Bissonnette
C. Thoma
James G. Krueger
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LB1140 Treatment with BI 655130, an anti-interleukin-36 receptor antibody, in patients with generalized pustular psoriasis, is associated with the downregulation of biomarkers linked to innate, Th1/Th17, and neutrophilic pathways
2019
Journal of Investigative Dermatology
Patrick Baum
Sudha Visvanathan
S. Bossert
B. Lang
Ramona Schmid
Sandra Garcet
Steven J. Padula
Hervé Bachelez
C. Thoma
James G. Krueger
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